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Онкологическая колопроктология

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АДЪЮВАНТНАЯ ХИМИОТЕРАПИЯ ПОСЛЕ ХИМИОЛУЧЕВОГО ЛЕЧЕНИЯ РАКА ПРЯМОЙ КИШКИ

https://doi.org/10.17650/2220-3478-2014-0-2-5-12

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Аннотация

Сочетание хирургического и предоперационного химиолучевого лечения является основой лечебной тактики у больных раком прямой кишки начиная со стадии cT3 или cN+. Внедрение в клинику данного подхода значимо снизило частоту рецидивов болезни и привело к улучшению общей выживаемости только при условии выполнения радикального хирургического лечения. Прогрессирование заболевания у большинства больных раком прямой кишки реализуется через отдаленное метастазирование, что диктует необходимость совершенствования системной терапии. Однако к настоящему времени не было доказательной базы эффективности назначения адъювантной химиотерапии (АХТ) после предоперационного химиолучевого лечения больных раком прямой кишки. Настоящий обзор литературы посвящен анализу результатов проспективных и ретроспективных исследований, пытавшихся ответить на вопрос об эффективности АХТ у больных раком прямой кишки после проведенного предоперационного лечения.

Об авторах

М. Ю. Федянин
ФГБУ «Российский онкологический научный центр им. Н. Н. Блохина» РАМН, Москва
Россия
Отделение клинической фармакологии и химиотерапии


А. А. Трякин
ФГБУ «Российский онкологический научный центр им. Н. Н. Блохина» РАМН, Москва
Россия
Отделение клинической фармакологии и химиотерапии


С. А. Тюляндин
ФГБУ «Российский онкологический научный центр им. Н. Н. Блохина» РАМН, Москва
Россия
Отделение клинической фармакологии и химиотерапии


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Для цитирования:


Федянин М.Ю., Трякин А.А., Тюляндин С.А. АДЪЮВАНТНАЯ ХИМИОТЕРАПИЯ ПОСЛЕ ХИМИОЛУЧЕВОГО ЛЕЧЕНИЯ РАКА ПРЯМОЙ КИШКИ. Онкологическая колопроктология. 2014;(2):5-12. https://doi.org/10.17650/2220-3478-2014-0-2-5-12

For citation:


Fedyanin M.Y., Tryakin A.A., Tjulandin S.A. ADJUVANT CHEMOTHERAPY AFTER RECTAL CANCER CHEMORADIOTHERAPY. Colorectal Oncology. 2014;(2):5-12. (In Russ.) https://doi.org/10.17650/2220-3478-2014-0-2-5-12

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ISSN 2220-3478 (Print)
ISSN 2413-0583 (Online)